Jon R. Cohen, M.D. Chief Executive Officer & Director | Talkspace
Choosing the right medication for anxiety involves careful consideration, as various drugs offer different benefits and risks. Two commonly prescribed medications are Hydroxyzine Pamoate and Xanax. Although both address anxiety, they differ significantly in their mechanism of action, suitability for long-term use, and potential for misuse or addiction.
Hydroxyzine is an antihistamine that provides a non-addictive option for anxiety relief. Xanax, a benzodiazepine often referred to as a "Benzo," is effective for short-term management but has a higher risk of dependence with prolonged use. Both medications require specific prescriptions and dosages guided by healthcare providers to ensure safe usage.
Dr. Dion Metzger, MD, a Talkspace therapist, explains: “Xanax is a very potent calming medication. It works fast and for a short period of time (several hours), which makes it a high risk for dependence." He notes that patients may develop tolerance over time, requiring higher doses to achieve the same effect.
Hydroxyzine offers sedative effects without addiction risks and can be used to treat allergies alongside anxiety disorders like generalized anxiety disorder (GAD). Xanax acts by enhancing gamma-aminobutyric acid (GABA) activity in the brain, making it suitable for acute anxiety episodes or panic attacks due to its fast onset of action.
The potential side effects of both medications include dizziness and drowsiness; however, Hydroxyzine might cause blurred vision while Xanax could lead to memory issues. Withdrawal symptoms also vary between them; Hydroxyzine poses lower withdrawal risks compared to Xanax's severe symptoms such as insomnia or seizures if not tapered correctly.
For those considering these medications: “Hydroxyzine is not as potent as Xanax and does not have a risk for dependence,” says Dr. Metzger. It’s often preferred when there's concern about substance abuse history.
Both drugs provide quick relief—Xanax within 20-30 minutes—and are generally intended for short-term use due to their side effects or dependency concerns.
When deciding between these options, consider factors like individual needs and medical history. Hydroxyzine may be better suited for generalized anxiety disorder or when there’s substance abuse history; whereas Xanax might be more appropriate during acute panic episodes demanding immediate relief.
Professional guidance from healthcare providers ensures proper treatment alignment with personal circumstances. Online psychiatry services like Talkspace offer convenient access to licensed experts who can help manage anxiety through appropriate prescriptions tailored specifically toward each patient’s unique situation.